Crohn’s disease (CD) is a chronic, disabling gastrointestinal disease with a rising incidence and prevalence.1 Affecting approximately 1 in 300 people in the Western world, CD typically evolves from an inflammatory process into penetrating and fibrostenotic disease. The end result is often surgical resection, either due to disease-related complications or progression to medically refractory disease. The cumulative risk of surgery in patients with CD at 1, 5, and 10 years is estimated to be 16.3%, 33.3%, and 46.6%, respectively.