Daily Archives: January 5, 2017
A Rare Endoscopic Clue to a Common Clinical Condition
Question: A 64-year-old woman presented to a local emergency department after noting large-volume passage of bright red blood from her colostomy site over several days. She denied any associated abdominal pain, recent changes in bowel pattern, nausea,… Continue reading
A Rare Endoscopic Clue to a Common Clinical Condition
Question: A 64-year-old woman presented to a local emergency department after noting large-volume passage of bright red blood from her colostomy site over several days. She denied any associated abdominal pain, recent changes in bowel pattern, nausea,… Continue reading
Choline Kinase Alpha Mediates Interactions Between the Epidermal Growth Factor Receptor and mTORC2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression
Choline kinase alpha (CHKA) catalyzes conversion of choline to phosphocholine and can contribute to carcinogenesis. Little is known about the role of CHKA in the pathogenesis of hepatocellular carcinoma (HCC). Continue reading
Choline Kinase Alpha Mediates Interactions Between the Epidermal Growth Factor Receptor and mTORC2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression
Choline kinase alpha (CHKA) catalyzes conversion of choline to phosphocholine and can contribute to carcinogenesis. Little is known about the role of CHKA in the pathogenesis of hepatocellular carcinoma (HCC). Continue reading
Western Dietary Pattern Increases, Whereas Prudent Dietary Pattern Decreases, Risk of Incident Diverticulitis in a Prospective Cohort Study
Dietary fiber is implicated as a risk factor for diverticulitis. Analyses of dietary patterns may provide information on risk beyond those of individual foods or nutrients. We examined whether major dietary patterns are associated with risk of incident… Continue reading
Western Dietary Pattern Increases, Whereas Prudent Dietary Pattern Decreases, Risk of Incident Diverticulitis in a Prospective Cohort Study
Dietary fiber is implicated as a risk factor for diverticulitis. Analyses of dietary patterns may provide information on risk beyond those of individual foods or nutrients. We examined whether major dietary patterns are associated with risk of incident… Continue reading
Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice
The role of the intestine in the maintenance of cholesterol homeostasis is increasingly recognized. Fecal excretion of cholesterol is the last step in the atheroprotective reverse cholesterol transport pathway, to which biliary and transintestinal chol… Continue reading
Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice
The role of the intestine in the maintenance of cholesterol homeostasis is increasingly recognized. Fecal excretion of cholesterol is the last step in the atheroprotective reverse cholesterol transport pathway, to which biliary and transintestinal chol… Continue reading