Monthly Archives: January 2017
Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice
Stool samples from patients with colorectal cancer (CRC) have a higher abundance of Peptostreptococcus anaerobius than stool from individuals without CRC, based on metagenome sequencing. We investigated whether P anaerobius contributes to colon tumor f… Continue reading
Exam 5: American Gastroenterological Association Institute Technical Review on Initial Testing and Management of Acute Liver Disease
Exam 4: American Gastroenterological Association Institute Guidelines for the Diagnosis and Management of Acute Liver Failure
Exam 4: American Gastroenterological Association Institute Guidelines for the Diagnosis and Management of Acute Liver Failure
Full-spectrum Endoscopy Improves Surveillance for Dysplasia in Patients With Inflammatory Bowel Diseases
Inflammatory bowel diseases (IBD) increase the risk of colorectal cancer. Surveillance colonoscopy with chromoendoscopy is recommended, but conventional forward-viewing colonoscopy (FVC) detects dysplasia with low levels of sensitivity. Full-spectrum e… Continue reading
Full-spectrum Endoscopy Improves Surveillance for Dysplasia in Patients With Inflammatory Bowel Diseases
Inflammatory bowel diseases (IBD) increase the risk of colorectal cancer. Surveillance colonoscopy with chromoendoscopy is recommended, but conventional forward-viewing colonoscopy (FVC) detects dysplasia with low levels of sensitivity. Full-spectrum e… Continue reading
Autophagy is Required for Activation of Pancreatic Stellate Cells, Associated With Pancreatic Cancer Progression and Promotes Growth of Pancreatic Tumors in Mice
Pancreatic stellate cells (PSCs) change from a quiescent to activated state in the tumor environment and secrete extracellular matrix (ECM) molecules and cytokines to increase the aggressiveness of tumors. However, it is not clear how PSCs are activate… Continue reading
Optogenetic demonstration of functional innervation of mouse colon by neurons derived from transplanted neural cells
Cell therapy offers the potential to treat gastrointestinal motility disorders caused by diseased or absent enteric neurons. We examined whether neurons generated from transplanted enteric neural cells provide a functional innervation of bowel smooth m… Continue reading
Optogenetic demonstration of functional innervation of mouse colon by neurons derived from transplanted neural cells
Cell therapy offers the potential to treat gastrointestinal motility disorders caused by diseased or absent enteric neurons. We examined whether neurons generated from transplanted enteric neural cells provide a functional innervation of bowel smooth m… Continue reading
Mesenchymal Cells in Colon Cancer
Mesenchymal cells in the intestine comprise a variety of cell types, of diverse origins, functions, and molecular markers. They provide mechanical and structural support and have important functions during intestinal organogenesis, morphogenesis, and h… Continue reading