Daily Archives: February 15, 2017
Bile acid control of metabolism and inflammation in obesity, type 2 diabetes, dyslipidemia and NAFLD
Bile acids are signaling molecules, which coordinately regulate metabolism and inflammation via the nuclear farnesoid X receptor (FXR) and the Takeda G protein-coupled receptor 5 (TGR5). These receptors activate transcriptional networks and signaling c… Continue reading
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“Is there an optimal diet for weight management and metabolic health?”
Individuals can lose body weight and improve health status on a wide range of energy (calorie) restricted dietary interventions. In this paper, we have reviewed the effectiveness of the most commonly utilized diets, including low-fat, low-carbohydrate … Continue reading
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Recent advances in human genetics and epigenetics of adiposity: pathway to precision medicine?
Obesity is a heritable trait that contributes to substantial global morbidity and mortality. Here, we summarize findings from the last decade of genetic and epigenetic research focused on unravelling the underpinnings of adiposity. More than 140 geneti… Continue reading
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