Monthly Archives: February 2017

Menopausal Hormone Therapy is Associated With Increased Risk of Fecal Incontinence in Women After Menopause

Low estrogen levels could contribute to development of fecal incontinence (FI) in women after menopause by altering neuromuscular continence mechanisms. However, studies have produced conflicting results on the association between menopausal hormone th… Continue reading

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SLC39A6 Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-kinase Signaling, and Upregulating Genes That Regulate Metastasis

A common variant in the solute carrier family 39 member 6 gene (SLC39A6) has been associated with survival times of patients with esophageal squamous-cell carcinoma (ESCC). We investigated the function of SLC39A6 and ways in which this variant affects … Continue reading

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Timely use of Probiotics in Hospitalized Adults Prevents Clostridium difficile Infection: a Systematic Review with Meta-Regression Analysis

Systematic reviews have provided evidence for the efficacy of probiotics in preventing Clostridium difficile infection (CDI), but guidelines do not recommend probiotic use for prevention of CDI. We performed an updated systematic review to help guide c… Continue reading

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Endoscopic Bariatric and Metabolic Therapies: New and Emerging Technologies

Endoscopic Bariatric and Metabolic Therapies (EBMT) are a new addition to the treatment arsenal for obesity. These include devices which are placed or removed via flexible endoscopy, and procedures which utilize instruments that require flexible endosc… Continue reading

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Practical Use of Pharmacotherapy for Obesity

Obesity management requires a multidisciplinary approach, as there are many factors that contribute to the development of obesity as well as the preservation of excess weight once it has been gained. Diet, exercise and behavior modification are key com… Continue reading

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Risk of obesity-related cardiometabolic complications in special populations: a crisis in Asians

The prospect of significant increase in global health-related costs associated with high cardiometabolic complications of obesity in Asians has encouraged more attention to the problem of growing obesity prevalence in these populations. While these stu… Continue reading

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Risk of obesity-related cardiometabolic complications in special populations: a crisis in Asians

The prospect of significant increase in global health-related costs associated with high cardiometabolic complications of obesity in Asians has encouraged more attention to the problem of growing obesity prevalence in these populations. While these stu… Continue reading

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Blaming the brain for obesity: Integration of hedonic and homeostatic mechanisms

The brain plays a key role in the controls of energy intake and expenditure and many genes associated with obesity are expressed in the central nervous system. Technological and conceptual advances in both basic and clinical neurosciences have expanded… Continue reading

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Blaming the brain for obesity: Integration of hedonic and homeostatic mechanisms

The brain plays a key role in the controls of energy intake and expenditure and many genes associated with obesity are expressed in the central nervous system. Technological and conceptual advances in both basic and clinical neurosciences have expanded… Continue reading

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Transforming Gastroenterology Care With Telemedicine

Healthcare is changing rapidly, so we must change with the times to develop more efficient, practical, cost-effective and, importantly, high-quality methods to care for patients. We teach medial students that optimal patient care requires face to face … Continue reading

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