Monthly Archives: March 2017

Question: A 67-year-old woman with lichen planus involving the skin was referred for evaluation of progressive solid food dysphagia for 10 years. There was a documented 10-lbs weight loss in the last 3 months. She described an increase in frequency of meats and breads sticking in the substernal area requiring liquids to facilitate food bolus passage. She had undergone annual upper endoscopies for >10 years that showed erosive esophagitis and esophageal candidiasis. A distal esophageal luminal stenosis was seen on several occasions. Continue reading →

Question: A 67-year-old woman with lichen planus involving the skin was referred for evaluation of progressive solid food dysphagia for 10 years. There was a documented 10-lbs weight loss in the last 3 months. She described an increase in frequency of meats and breads sticking in the substernal area requiring liquids to facilitate food bolus passage. She had undergone annual upper endoscopies for >10 years that showed erosive esophagitis and esophageal candidiasis. A distal esophageal luminal stenosis was seen on several occasions. Continue reading →

Recent advances in gene editing have enabled us to easily manipulate DNA using CRISPR (clustered regularly interspaced short palindromic repeats)/CAS9 (CRISPR-associated protein 9) technology.1 CRISPR/CAS9 is an endonuclease that exploits the DNA doubl… Continue reading →

There is a global increase in the incidence of liver cirrhosis, and although specific disease therapies are available, there is a large population of patients with advanced cirrhosis who are prone to regular decompensation and an increased risk of live… Continue reading →

Question: A 52-year-old woman presented to the emergency department with severe, diffuse abdominal pain of acute onset radiating to her left shoulder and neck. Her medical history was remarkable for cholecystitis and her surgical history was notable fo… Continue reading →

Question: A 52-year-old woman presented to the emergency department with severe, diffuse abdominal pain of acute onset radiating to her left shoulder and neck. Her medical history was remarkable for cholecystitis and her surgical history was notable fo… Continue reading →

Research during training complements learning, helping to develop, and reinforcing core competencies. Research is also associated with career satisfaction and superior clinical performance.1,2 Although scholarly activity is a required component of post… Continue reading →