Daily Archives: April 1, 2017

Question: A 64-year-old man presented for his first average-risk screening colonoscopy. The patient reported occasional abdominal cramps, but was otherwise without any symptoms or medical problems. Physical examination was unremarkable, and review of … Continue reading →

Question: A 76-year-old man presented to the emergency department complaining of exertional dyspnea in the previous 3 weeks and an episode of presyncope that day. He denied orthopnea, paroxysmal nocturnal dyspnea, and precordial pain. On further ques… Continue reading →

We read with interest the article by Lembo et al1 evaluating the safety and efficacy of repeat treatment with rifaximin in patients with diarrhea-predominant irritable bowel syndrome (IBS-D). The authors found that repeat rifaximin treatment was effic… Continue reading →

The 2008 Journal of the National Cancer Institute guidelines recommend time to progression (TTP) in the randomized phase II setting for intermediate hepatocellular carcinoma (HCC).1 PREMIERE complied with the recommendation and was initiated in 2009. I… Continue reading →

The comments by Itzkowitz and Ahlquist made us recall George Box’s saying that “all models are wrong but some are useful.” We acknowledge that our model is a simplification of reality, and we agree that its assumptions must be appreciated, but we… Continue reading →

We would like to congratulate the authors for the first randomized phase 2 study comparing the effects of conventional transarterial chemoembolization (cTACE) and Y90 radioembolization (Y90) in patients with hepatocellular carcinoma (HCC).1 This study … Continue reading →