Daily Archives: April 3, 2017

Question: A 45-year-old man with a 22-year history of Crohn’s disease was admitted for muscular weakness, and bilateral groin and shoulder pain. On examination the patient presented with waddling walk, proximal muscular weakness, and a positive Gower… Continue reading →

Question: A 50-year-old man presented with complaint of recurrent nonbilious vomiting for 4 months and a weight loss of 66 pounds in the same time frame. Physical examination revealed a tympanitic mass in the epigastrium. Laboratory testing revealed no… Continue reading →

Question: A 62-year-old man with a history of umbilical hernia repair presented with a 1-day history of abdominal pain, nausea, and vomiting. He endorsed constipation but no obstipation. He denied any melena or hematochezia. Owing to a history of alter… Continue reading →

Dai et al provided comments on the use of the nonsystemic antibiotic rifaximin for diarrhea-predominant irritable bowel syndrome (IBS-D) and data from the TARGET 3 repeat treatment trial of rifaximin for adults with IBS-D.1 Specifically, concerns wer… Continue reading →

Question: A 53-year-old man presented to the emergency department with 2 hours of upper abdominal pain. Vital signs were unremarkable. He had no underlying disease, but had taken some unknown Chinese herbs for 1 year. Physical examination revealed palp… Continue reading →

Question: A 68-year-old man with hypertension, multiple sclerosis, and neurogenic bladder underwent an inpatient bowel cleansing owing to immobility for a routine screening colonoscopy. The patient was asymptomatic, had no complaints, and no other acti… Continue reading →

Question: A 57-year-old woman had an incidentally detected pancreatic mass and multiple liver lesions diagnosed on her annual checkup. She was previously healthy and denied any surgery. At presentation, the laboratory findings and tumor markers were wi… Continue reading →

We read with interest the recent study by Salem et al1 providing evidence from a randomized phase II trial of patients with hepatocellular carcinoma (HCC) that Y90 radioembolization is associated with significantly longer median time to progression (T… Continue reading →

Question: A 45-year-old Indian female presented with recurrent episodes of acute pancreatitis for seven months. Last episode was one month back. Her clinical examination was unremarkable. There was no history of alcohol or drug intake. Her routine bloo… Continue reading →

We read with interest the manuscript from Martínez-Cardús et al,1 which defines methylation heterogeneity, both interpatient and intratumoral, using multiregional sampling in colorectal cancer (CRC). The authors show that samples will cluster accord… Continue reading →