Daily Archives: April 28, 2017
Information for Authors and Readers
Gastroenterology is the premiere journal in the field of gastrointestinal disease and is led by an internationally renowned board of editors. As the official journal of the AGA Institute, Gastroenterology delivers up-to-date and authoritative coverag… Continue reading
How to Get an Education in Inflammatory Bowel Disease During Fellowship: Expectations and Realities
For gastroenterology (GI) fellows, exposure to inflammatory bowel disease (IBD) during training will vary widely based on institutional expertise, educational standards, personal interest, and resources to attend regional and national meetings. This ex… Continue reading
Surveillance for One or Two Small Adenomas: Low Risk Is Really Low Risk
The optimal timing for postpolypectomy surveillance for low-risk adenomas, defined as 1-2 small tubular adenomas, has remained a challenge for clinicians and guideline developers over past 4 decades. From the 1970s to the 1990s, it was common practice for clinicians to recommend annual surveillance for even a small adenoma (ie, <10 mm), because of the perceived knowledge that all adenomas were premalignant.1 In 1993, the National Polyp Study helped to provide much needed evidence for the timing of postpolypectomy surveillance by showing there was no difference in the risk of finding an advanced adenoma at 1 and 3 years after the baseline colonoscopy versus 3 years alone. Continue reading
Predictors of the Clinical Course of Primary Sclerosing Cholangitis
The clinical course of primary sclerosing cholangitis (PSC) is highly variable. Some patients are asymptomatic for years, whereas others develop end-stage liver disease or cholangiocarcinoma (CCA) shortly after diagnosis.1–4 Previous studies have rep… Continue reading
Probiotics for Prevention of Clostridium difficile Infection in Hospitalized Patients: Is the Jury Still Out?
The incidence of Clostridium difficile infection (CDI) has increased in the past decade, despite intensified efforts at prevention including infection control and antimicrobial stewardship.1 This has led to the exploration of additional means to reduce… Continue reading
Validation of Antibody-based Strategies for Diagnosis of Pediatric Celiac Disease Without Biopsy
A diagnosis of celiac disease is made based on clinical, genetic, serologic, and duodenal morphology features. Recent pediatric guidelines, based largely on retrospective data, propose omitting biopsy analysis for patients with concentrations of immuno… Continue reading
Multidisciplinary Care in Hepatocellular Carcinoma: Where Do We Go From Here?
Over the last 4 decades, advances in surgical techniques, locoregional therapy imaging, and systemic therapy have significantly improved overall survival (OS) in hepatocellular carcinoma (HCC).1 HCC’s complex nature, influenced by tumor burden, liver… Continue reading