Daily Archives: May 25, 2017

American Gastroenterological Association Institute Guideline on the Role of Elastography in the Evaluation of Liver Fibrosis

This document represents the official recommendations of the American Gastroenterological Association (AGA) on the role of vibration-controlled transient elastography (VCTE) in the evaluation of liver fibrosis. The guideline was developed by the Clinic… Continue reading

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Hepatitis C Virus Infection Care Pathway—A Report From the American Gastroenterological Association Institute HCV Care Pathway Work Group

Chronic hepatitis C virus (HCV) infection is a common condition that affects more than 2.7 million individuals in the US.1 New direct acting antiviral (DAA) treatments offer an unprecedented opportunity to cure HCV. In clinical trials as well as clinic… Continue reading

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In Vivo Imaging Reveals Existence of Crypt Fission and Fusion in Adult Mouse Intestine

The intestinal epithelium is a repetitive sheet of crypt and villus units with stem cells at the bottom of the crypts. During postnatal development, crypts multiply via fission, generating 2 daughter crypts from 1 parental crypt. In the adult intestine… Continue reading

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Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota

Intestinal epithelial homeostasis is maintained by complex interactions among epithelial cells, commensal gut microorganisms, and immune cells. Disruption of this homeostasis is associated with disorders such as inflammatory bowel disease (IBD), but th… Continue reading

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