Monthly Archives: May 2017

Esophagogastroduodenoscopy (EGD) is commonly used to detect upper gastrointestinal (GI) neoplasms. However, there is little evidence that longer examination time increases rate of detection of upper GI neoplasia. We investigated the association between… Continue reading →

Question: A 23-year-old woman with a history of acid reflux, trichotillomania and trichophagia with reported last ingestion four years prior presented with a three week history of postprandial epigastric and right upper quadrant pain, nausea and vomiti… Continue reading →

We thank the authors for their interest in our original article.1 We have read their argument and we offer responses on 2 main points: (1)“The challenges with studying populations of non-European ancestry remains one of terminology” and (2) “So a… Continue reading →

Question: A 58-year-old woman presented with multiple episodes of coffee ground emesis with no associated melena or hematochezia. The patient reported no prior history of gastrointestinal bleeding. She had multiple medical comorbidities, including hype… Continue reading →

Probiotics can reduce symptoms of irritable bowel syndrome (IBS), but little is known about their effects on psychiatric comorbidities. We performed a prospective study to evaluate the effects of Bifidobacterium longum NCC3001 (BL) on anxiety and depre… Continue reading →

Among subjects screened for colorectal cancer (CRC) by the guaiac fecal occult blood test, interval cancers develop in 48%–55% of the subjects. Data are limited on how many persons screened by fecal immunochemical tests (FIT), over multiple rounds, d… Continue reading →

Question: A 62-year-old woman presented with sudden abdominal pain in the left lower quadrant for 2 days. The needle-like abdominal pain was aggravated when changing body position and during defecation, but remitted when lying flat. She had a history o… Continue reading →

Primary myelofibrosis is a form of myeloproliferative neoplasm characterized by stem-cell derived clonal proliferation, resulting in bone marrow fibrosis, splenomegaly and extramedullary haematopoiesis, with portal hypertension (PHT) occuring in 10%–… Continue reading →

Question: A 24-year-old man presented to us with a 6-month history of epigastric pain aggravated by meals. Additional history revealed no radiation of the pain or any associated symptoms of loss of appetite, loss of weight, use of nonsteroidal antiinflammatory drugs before the onset of pain, recent trauma, or surgery. General physical and systemic examinations were unremarkable. Laboratory testing showed normal serum amylase and lipase levels. His blood sugars and glycated hemoglobin A1C (HbA1C) were also within normal limits (fasting blood sugar, 96 mg/dL [normal, <100], postprandial blood sugar, 116 mg/dL [normal, <200), HbA1c, 5.4 [normal range, 4.2–6.2]). Continue reading →