Monthly Archives: May 2017

We congratulate van Engelenburg-van Lonkhuyzen et al1 on their study on the effectiveness of pelvic physiotherapy in children with functional constipation. This randomized, controlled trial showed that pelvic physiotherapy was more effective than stan… Continue reading →

Liver cirrhosis is complicated by bleeding from portal hypertension but also by portal vein thrombosis (PVT). PVT occurs in about 20%–50% of patients with cirrhosis, and is a warning sign for poor outcome. It is a challenge to treat patients with cir… Continue reading →

We appreciate the interest of Summeren et al in our study and their careful and thorough discussion of the potential caveats and context required to interpret our findings. Continue reading →

Algorithms for diagnosis of malignant common bile duct (CBD) stenoses are complex and lack accuracy. Malignant tumors secrete large numbers of extracellular vesicles (EVs) into surrounding fluids; EVs might therefore serve as biomarkers for diagnosis. … Continue reading →

Question: A 69-year-old renal transplant patient was hospitalized because of persistent dyspepsia, anorexia with progressive weight loss, and intermittent loose stools. She received a cadaveric kidney 18 months ago complicated by an acute antibody-medi… Continue reading →

Studies of Clostridium difficile infections (CDIs) among individuals with inflammatory bowel disease (IBD) have used data from single centers or CDI administrative data codes of limited diagnostic accuracy. We determined the incidence, risk factors, an… Continue reading →

We read with great interest the original article by Brant et al.1 The discovery of African American (AA)-specific loci and loci that are shared between ethnic groups highlight the importance of studying inflammatory bowel disease in other populations … Continue reading →

Question: A 59-year-old man presented to the clinic with 5 days of right upper quadrant abdominal pain, pruritus, and scleral icterus. The pain was constant, dull, nonradiating, and not associated with fever or rigors. His medical history pertinent for… Continue reading →

“Tis after death that we measure men”—James Barron Hope Continue reading →