Monthly Archives: May 2017

Ruxolitinib for the Treatment of Portal Hypertension in a Patient With Primary Myelofibrosis

Primary myelofibrosis is a form of myeloproliferative neoplasm characterized by stem-cell derived clonal proliferation, resulting in bone marrow fibrosis, splenomegaly and extramedullary haematopoiesis, with portal hypertension (PHT) occuring in 10%–… Continue reading

Posted in News | Comments Off on Ruxolitinib for the Treatment of Portal Hypertension in a Patient With Primary Myelofibrosis

Proton Pump Inhibitor Administration Triggers Encephalopathy in Cirrhotic Patients by Modulating Blood–Brain Barrier Drug Transport

We read with interest the article by Tsai et al1 in a recent issue of Gastroenterology, which highlights the influence of proton pump inhibitors (PPIs) use on encephalopathy occurrence in cirrhotic patients. This case control study performed in a larg… Continue reading

Posted in News | Comments Off on Proton Pump Inhibitor Administration Triggers Encephalopathy in Cirrhotic Patients by Modulating Blood–Brain Barrier Drug Transport

Covering the Cover

In a small study of patients with esophagitis or Barrett’s esophagus, a weight-lifter belt increased postprandial gastroesophageal reflux. Continue reading

Posted in News | Comments Off on Covering the Cover

Atlas of Esophageal Disease and Intervention: A Multidisciplinary Approach

I read with great interest this hardback book, which is compiled as an atlas of esophageal diseases. The authors should be congratulated for a very nice product, which I am sure will serve as a resource to many interested in better understanding of eso… Continue reading

Posted in News | Comments Off on Atlas of Esophageal Disease and Intervention: A Multidisciplinary Approach

Early Detection of Hepatocellular Carcinoma after Treatment With Direct-Acting Antivirals: Selection Bias or Biologically Plausible?

Conti F, Buonfiglioli F, Scuteri A, et al. Early occurrence and recurrence of hepatocellular carcinoma in HCV-related cirrhosis treated with direct-acting antivirals. J Hepatol 2016;65(4):727-733. Continue reading

Posted in News | Comments Off on Early Detection of Hepatocellular Carcinoma after Treatment With Direct-Acting Antivirals: Selection Bias or Biologically Plausible?