Daily Archives: June 1, 2017
Late Recurrence of Barrett’s Esophagus After Complete Eradication of Intestinal Metaplasia is Rare: Final Report From Ablation in Intestinal Metaplasia Containing Dysplasia Trial
The goal of treatment for Barrett’s esophagus (BE) with dysplasia is complete eradication of intestinal metaplasia (CEIM). The long-term durability of CEIM has not been well characterized, so the frequency and duration of surveillance are unclear. We… Continue reading
Effects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children With Obesity
Consumption of sugar is associated with obesity, type 2 diabetes mellitus, nonalcoholic fatty liver disease, and cardiovascular disease. The conversion of fructose to fat in liver (de novo lipogenesis [DNL]) may be a modifiable pathogenetic pathway. We determined the effect of 9 days of isocaloric fructose restriction on DNL, liver fat, visceral fat (VAT), subcutaneous fat, and insulin kinetics in obese Latino and African American children with habitual high sugar consumption (fructose intake >50 g/d). Continue reading
Cullen’s sign – not always acute pancreatitis
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We thank Cannon and Henegan, as well as Kanis and van der Woude, for their comments on our paper “Outcomes of Pregnancies for Women Undergoing Endoscopy While They Were Pregnant.”1 Continue reading
Crohn’s and a Cough: Connecting the Dots
Question: A 22-year-old man with Crohn’s ileocolitis was referred for chronic cough and recurrent left lower lobe (LLL) pneumonia. He was diagnosed with Crohn’s ileocolitis 2 years ago, and briefly treated with oral mesalazine before being switched… Continue reading
The Need for Appropriate Comparisons: A Response to Ravi et al
Over the past 2 decades, multiple studies have clearly demonstrated that eradication of hepatitis C virus (HCV; ie, sustained virologic response [SVR]) with interferon (IFN)-based treatment is associated with a significant decrease in the risk of the d… Continue reading
Effects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children with Obesity
Consumption of sugar is associated with obesity, type 2 diabetes mellitus, non-alcoholic fatty liver disease, and cardiovascular disease. The conversion of fructose to fat in liver (de novo lipogenesis, DNL) may be a modifiable pathogenetic pathway. We… Continue reading
Endoscopy for Inflammatory Bowel Disease During Pregnancy: Only When There Is a Strong Indication
With great interest we have read the study by Ludvigsson et al,1 published in the October issue of Gastroenterology, who performed a population-based study to examine the risks of endoscopy during pregnancy. This nationwide Swedish study showed that exposure to any endoscopy during pregnancy, independent of trimester and indication, was related to preterm birth and children born small for gestational age. However, when restricting data to women without a gastrointestinal disease, risk estimates decreased, and when limiting controls to women with endoscopy <1 year before or after pregnancy, endoscopy was not associated with any adverse pregnancy outcome. Continue reading
Late Recurrence of Barrett’s Esophagus After Complete Eradication of Intestinal Metaplasia is Rare: Final Report From Ablation in Intestinal Metaplasia Containing Dysplasia Trial
The goal of treatment for Barrett’s esophagus (BE) with dysplasia is complete eradication of intestinal metaplasia (CEIM). The long-term durability of CEIM has not been well characterized, so the frequency and duration of surveillance are unclear. We… Continue reading
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Occult hepatitis C virus (HCV) infection (OCI) is defined as the presence of the HCV genome in either liver tissue or peripheral blood monocytes, despite constantly undetectable HCV-RNA in serum. The prevalence of OCI has been thought extremely rare in… Continue reading