Daily Archives: June 2, 2017

Practice Patterns for Cholecystectomy After Endoscopic Retrograde Cholangiopancreatography for Patients With Choledocholithiasis

Cholecystectomy (CCY) after an episode of choledocholithiasis requiring endoscopic retrograde cholangiopancreatography (ERCP) with stone extraction reduces recurrent biliary events compared to expectant management. We studied practice patterns for perf… Continue reading

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Association Between Proton Pump Inhibitor Use and Risk of Progression of Chronic Kidney Disease

Proton pump inhibitors (PPI) have been associated with acute kidney injury and recent studies suggest that they may be associated with the risk of chronic kidney disease (CKD). Continue reading

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Regulator of Calcineurin 1 Gene Isoform 4, Down-regulated in Hepatocellular Carcinoma, Prevents Proliferation, Migration, and Invasive Activity of Cancer Cells and Metastasis of Orthotopic Tumors by Inhibiting Nuclear Translocation of NFAT1

Individuals with Down syndrome have a low risk for many solid tumors, prompting the search for tumor suppressor genes on human chromosome 21 (HSA21). We aimed to identify and explore potential mechanisms of tumor suppressors on HSA21 in hepatocellular … Continue reading

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Risk Stratification for Covert Invasive Cancer Among Patients Referred for Colonic Endoscopic Mucosal Resection: A Large Multicenter Cohort

Among patients with large colorectal sessile polyps or laterally spreading lesions, it is important to identify those at risk for submucosal invasive cancer (SMIC). Lesions with overt endoscopic evidence of SMIC are referred for surgery, although those… Continue reading

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Exam 2: Increased Risk of Colorectal Cancer in Patients With Multiple Serrated Polyps and Their First-degree Relatives

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Right Upper Abdominal Distension and Discomfort Caused by a Massive Hepatic Tumor

Question: A 42-year-old woman was admitted to our hospital with a 1-year history of right upper abdominal distension and discomfort that had worsened for the past month. She had no history of liver cirrhosis or chronic hepatitis B virus infection. Phys… Continue reading

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Presentation of a Rare Cystic Mass

Question: A 32-year-old woman with no past medical history presented to our medical center with 2 months of intermittent right upper quadrant pain. The pain started gradually, hurting primarily when lying on her right side. She had limited past medical… Continue reading

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Unusual Cause of Hematochezia

Question: A 73-year-old woman experienced 2 episodes of hematochezia 2 weeks before her admission. She had been treated for mild hypertension, and had a history of cholecystectomy, appendectomy, 2 C-sections, and unspecified pancreatic surgery 17 years… Continue reading

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Undesired Final of a Student’s Beer Drinking Duel

Question: In the early morning, a 22-year-old member of a fraternity presented at our emergency department with retrosternal pain and dysphagia. He had participated in a beer drinking duel and had drunk about 1.5 L of beer, divided into smaller portion… Continue reading

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Mimicking Gastric Natural Killer/T-Cell Lymphoma

Question: A 71-year-old woman with hypertension and dyslipidemia was referred to our hospital because of a high level of carbohydrate antigen (CA) 19-9 of 85 U/mL. She was asymptomatic and had no findings on physical assessment or blood tests, except a… Continue reading

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