Monthly Archives: June 2017
TEMPORARY REMOVAL: Accuracy of Tests for Antibodies Against Tissue-transglutaminase in Diagnosis of Celiac Disease, Without Biopsy
The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated.The full Elsevier Policy on Arti… Continue reading
Epigenome-wide Association Study Identifies Methylation Sites Associated With Liver Enzymes and Hepatic Steatosis
Epigenetic mechanisms might be involved in the regulation of liver enzyme level. We aimed to identify CpG sites at which DNA methylation levels are associated with blood levels of liver enzymes and hepatic steatosis. Continue reading
Agreement Between Magnetic Resonance Imaging Proton Density Fat Fraction Measurements and Pathologist-assigned Steatosis Grades of Liver Biopsies from Adults with Nonalcoholic Steatohepatitis
We assessed the diagnostic performance of magnetic resonance imaging (MRI) proton density fat fraction (PDFF) in grading hepatic steatosis and change in hepatic steatosis in adults with nonalcoholic steatohepatitis (NASH) in a multi-center study, using… Continue reading
Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features
The study defines the ∼25% population with molecular characteristics – including high infiltration of immune cells, expression of PD-1 and CD274 molecule (PD-L1), and active IFN-γ signaling – that highly resemble those of cancers most responsive to … Continue reading
Proton pump inhibitors decrease phlebotomy need in HFE hemochromatosis: double-blind randomized placebo-controlled trial
Intestinal Fungal Dysbiosis Associates With Visceral Hypersensitivity in Patients With Irritable Bowel Syndrome and Rats
Visceral hypersensitivity is one feature of irritable bowel syndrome (IBS). Bacterial dysbiosis might be involved in activation of nociceptive sensory pathways, but there have been few studies of the role of the mycobiome (the fungal microbiome) in dev… Continue reading
An Incidental Pancreatic Mass in a Young Woman
Question: A 37-year-old woman was admitted owing to a pancreatic mass, which was incidentally found at chest computed tomography (CT) scan for the evaluation of pneumonia 3 months before admission. She was asymptomatic and her family history was unrema… Continue reading
Impaired Intestinal Permeability Contributes to Ongoing Bowel Symptoms in Patients With Inflammatory Bowel Disease and Mucosal Healing
Many patients with inflammatory bowel diseases (IBD) have ongoing bowel symptoms of diarrhea or abdominal pain despite mucosal healing. We investigated whether impaired intestinal permeability contributes to these symptoms. Continue reading
Impaired Intestinal Permeability Contributes to Ongoing Bowel Symptoms in Patients With Inflammatory Bowel Disease and Mucosal Healing
Many patients with inflammatory bowel diseases (IBD) have ongoing bowel symptoms of diarrhea or abdominal pain despite mucosal healing. We investigated whether impaired intestinal permeability contributes to these symptoms. Continue reading