Monthly Archives: June 2017
A Selection of Best AGA Abstracts of DDW 2017
This is a summary of 12 abstracts selected for review during the Tuesday afternoon Best of DDW Session at DDW 2017. These abstracts were selected from the presentations at the Presidential Plenary, the Basic Science Plenary, and individual section plen… Continue reading
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When to Search for Occult Infection After Eradication of Hepatitis C?
We read with great interest the article by Elmasry et al on the detection of occult hepatitis C virus (HCV) infection (OCI) in patients with abnormal levels of serum aminotransferases despite a sustained virologic response (SVR), after treatment with … Continue reading
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A Summary of the 2016 James W. Freston Conference of the American Gastroenterological Association: Intestinal Metaplasia in the Esophagus and Stomach: Origins, Differences, Similarities and Significance
Metaplasia, wherein 1 type of adult tissue replaces another, is a consequence of chronic inflammation.1 Presumably, metaplasias develop and persist because they are more adept than the native tissue at resisting injury from the underlying inflammatory … Continue reading
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“Errare Humanum Est, Perseverare Autem Diabolicum”
Question: A 79-year-old man with no significant past medical history presented to the emergency department with a 2-day history of melena. He was hemodynamically stable and laboratory tests were unremarkable, except for normocytic anemia (hemoglobin, 9… Continue reading
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Exam 1: Altered Bowel Habits and Pelvic Fullness in a 75-Year-Old Woman
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Exam 1: Altered Bowel Habits and Pelvic Fullness in a 75-Year-Old Woman
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Regulator of Calcineurin 1 Gene Isoform 4, Downregulated in Hepatocellular Carcinoma, Prevents Proliferation, Migration, and Invasive Activity of Cancer Cells and Growth of Orthotopic Tumors by Inhibiting Nuclear Translocation of NFAT1
Individuals with Down syndrome have a low risk for many solid tumors, prompting the search for tumor suppressor genes on human chromosome 21 (HSA21). We aimed to identify and explore potential mechanisms of suppressors on HSA21 in hepatocellular carcin… Continue reading
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Regulator of Calcineurin 1 Gene Isoform 4, Downregulated in Hepatocellular Carcinoma, Prevents Proliferation, Migration, and Invasive Activity of Cancer Cells and Growth of Orthotopic Tumors by Inhibiting Nuclear Translocation of NFAT1
Individuals with Down syndrome have a low risk for many solid tumors, prompting the search for tumor suppressor genes on human chromosome 21 (HSA21). We aimed to identify and explore potential mechanisms of suppressors on HSA21 in hepatocellular carcin… Continue reading
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Late Recurrence of Barrett’s Esophagus After Complete Eradication of Intestinal Metaplasia is Rare: Final Report From Ablation in Intestinal Metaplasia Containing Dysplasia Trial
The goal of treatment for Barrett’s esophagus (BE) with dysplasia is complete eradication of intestinal metaplasia (CEIM). The long-term durability of CEIM has not been well characterized, so the frequency and duration of surveillance are unclear. We… Continue reading
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Effects of Dietary Fructose Restriction on Liver Fat, De Novo Lipogenesis, and Insulin Kinetics in Children With Obesity
Consumption of sugar is associated with obesity, type 2 diabetes mellitus, nonalcoholic fatty liver disease, and cardiovascular disease. The conversion of fructose to fat in liver (de novo lipogenesis [DNL]) may be a modifiable pathogenetic pathway. We determined the effect of 9 days of isocaloric fructose restriction on DNL, liver fat, visceral fat (VAT), subcutaneous fat, and insulin kinetics in obese Latino and African American children with habitual high sugar consumption (fructose intake >50 g/d). Continue reading
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