Monthly Archives: July 2017
Randomized Comparison of 3 High-level Disinfection and Sterilization Procedures for Duodenoscopes
The DISINFECTS trial is a prospective randomized trial investigating three methods of reprocessing duodenoscopes: standard high-level disinfection with ortho-phthalaldehyde disinfectant, standard high-level disinfection with a repeated (double) cycle of disinfectant exposure, and standard high-level disinfection followed by ethylene oxide gas sterilization. No significant difference was noted between these reprocessing methods with regard to proportion of duodenoscopes with MDRO contamination, or demonstrating ≥10 CFU or >0 CFU growth of any aerobic bacteria. Continue reading
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Influence of Metabolic Risk Factors on Risk of Hepatocellular Carcinoma and Liver-related Death in Men with Chronic Hepatitis B: A Large Cohort Study
Little is known about the absolute risk of hepatocellular carcinoma (HCC) and liver-disease related death, in association with metabolic risk factors, for patients with hepatitis B virus (HBV) infection. Continue reading
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Influence of Metabolic Risk Factors on Risk of Hepatocellular Carcinoma and Liver-related Death in Men with Chronic Hepatitis B: A Large Cohort Study
Little is known about the absolute risk of hepatocellular carcinoma (HCC) and liver-disease related death, in association with metabolic risk factors, for patients with hepatitis B virus (HBV) infection. Continue reading
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Vasoactive Intestinal Polypeptide and Mast Cells Regulate Increased Passage of Colonic Bacteria in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is associated with intestinal dysbiosis and symptoms of IBS develop following gastroenteritis. We aimed to study passage of live bacteria through the colonic epithelium, and determine the role of mast cells and vasoactive… Continue reading
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Vasoactive Intestinal Polypeptide and Mast Cells Regulate Increased Passage of Colonic Bacteria in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is associated with intestinal dysbiosis and symptoms of IBS develop following gastroenteritis. We aimed to study passage of live bacteria through the colonic epithelium, and determine the role of mast cells and vasoactive… Continue reading
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Avoidance of Cow’s Milk−Based Formula for At-Risk Infants Does Not Reduce Development of Celiac Disease: A Randomized Controlled Trial
Feeding during the first months of life might affect risk for celiac disease. Individuals with celiac disease or type 1 diabetes have been reported to have high titers of antibodies against cow’s milk proteins. Avoidance of cow’s milk−based formu… Continue reading
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Avoidance of Cow’s Milk-based Formula for At-risk Infants Does Not Reduce Development of Celiac Disease: a Randomized Controlled Trial
Feeding during first months of life might affect risk of celiac disease. Individuals with celiac disease or type 1 diabetes have been reported to have high titers of antibodies against cow´s milk proteins. Avoidance of cow’s milk-based formula for i… Continue reading
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First Identification of Biallelic Inherited DUOX2 Inactivating Mutations as a Cause of Very Early Onset Inflammatory Bowel Disease
By catalyzing generation of hydrogen peroxide (H202) in enterocytes, DUOX2 participates in innate defense against intestinal microbes.1,2 One monoallelic exonic variant of DUOX2 was recently found in 15 out of 19 Crohn disease-affected patients in a la… Continue reading
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