Question: A 67-year-old man with a history of chronic lymphocytic leukemia (CLL) complicated by recurrent bacterial infections presented to the outpatient clinic with an abrupt onset of altered bowel habits. He reported the urge to defecate several times per day, but only had occasional passage of small, semisolid stools. At baseline, he typically experienced having 1 to 2 large bowel movements per day. Screening colonoscopy was performed 3 years prior and was notable for a 4-mm tubular adenoma in the ascending colon, with an adequate bowel preparation noted.