Monthly Archives: August 2017
Exam 1: Detection, Diagnosis, and Resection of Sessile Serrated Adenomas and Polyps
Reply
Thank you, Dr Gin-Ho Lo, for your comments about our randomized controlled trial (RCT) of Doppler endoscopic probe (DEP) as a guide to improving risk stratification and definitive endoscopic hemostasis of severe nonvariceal upper gastrointestinal hemor… Continue reading
A Huge Mass in the Upper Esophagus
Question: A 56-year-old man with a history of mild dysphagia for 4 months experienced worsening of his symptoms when he caught a cold or was tired, but without nausea, vomiting, acid reflux, abdominal pain, or bloating. He had no history of diabetes me… Continue reading
A Case Report of a Child With Purpura, Severe Abdominal Pain, and Hematochezia
Question: A 5-year old Caucasian boy presented with sudden onset of diffuse purpuric and petechial skin lesions without fever at the pediatric department. The following days he developed diffuse abdominal pain with bloody stools (4-6 times a day). He a… Continue reading
Resistance-Associated Substitutions in Short Duration of Interferon-Free Direct-Acting Antivirals for Hepatitis C
We read with great interest the report of Gane et al.1 They evaluated the efficacy and safety of direct-acting antivirals, ledipasvir-sofosbuvir fixed dose combination, for chronic hepatitis C virus genotype 2 infection. The rate of sustained virologi… Continue reading
Transplant-Free Survival Rates After Covered Transjugular Intrahepatic Portosystemic Shunt
We acknowledge the challenges identified by the authors in the management of recurrent or refractory ascites.1 Although data identifying candidate suitability for transjugular intrahepatic portosystemic shunt (TIPSS) is satisfactory, the optimum timing… Continue reading
Reply
We thank Dr Yu and colleagues for their letter. We agree that the presence of baseline NS5A resistance-associated substitutions in patients with hepatitis C virus genotype 2 infection reduces the efficacy of ultrashort durations of ledipasvir-sofosbuvi… Continue reading
The Use of Doppler Endoscopic Probe in Hemostasis of Nonvariceal Gastrointestinal Bleeding: To Increase Efficacy or to Increase Work Load?
I read with interest the article by Jensen et al1 regarding the use of a Doppler endoscopic probe (DEP) in hemostasis of nonvariceal gastrointestinal bleeding. The authors demonstrated that use of a DEP can significantly reduce the rebleeding rate of … Continue reading
Altered Bowel Habits and Occult Gastrointestinal Bleeding in a 67-Year-Old Man
Question: A 67-year-old man with a history of chronic lymphocytic leukemia (CLL) complicated by recurrent bacterial infections presented to the outpatient clinic with an abrupt onset of altered bowel habits. He reported the urge to defecate several tim… Continue reading