Monthly Archives: August 2017
Exam 2: Stratification of Risk for Covert Invasive Cancer in Patients With Large Colonic Neoplasia in a Multi-Center Endoscopic Mucosal Resection Cohort
Exam 3: Practice Patterns for Cholecystectomy Following Endoscopic Retrograde Cholangio-Pancreatography for Patients With Choledocholithiasis
Exam 4: Guideline: Therapeutic Drug Monitoring
Liver Pathology for Clinicians
The difficult task of linking histology findings with the clinical picture daunts many beginning clinicians, and can be a source of frustration for seasoned practitioners as well. Resorting to review of detailed pathology textbooks, clinicopathologic c… Continue reading
Exam 5: Technical Review CME Questions: Therapeutic Drug Monitoring in IBD
Management of Gastroesophageal Reflux Disease
Management of GERD commonly starts with an empiric trial of proton pump inhibitor (PPI) therapy and complementary lifestyle measures, for patients without alarm symptoms. Optimization of therapy (improving compliance and timing of PPI doses), or increa… Continue reading
MFSD2A Promotes Endothelial Generation of Inflammation-resolving Lipid Mediators and Reduces Colitis in Mice
Alterations in signaling pathways that regulate resolution of inflammation (resolving pathways) contribute to pathogenesis of ulcerative colitis (UC). The resolution process is regulated by lipid mediators, such as those derived from the ω-3 docosahex… Continue reading
Why Would a Patient Complain of Dysphagia and Heartburn After Multiple Bariatric Surgeries?
Question: A 43-year-old woman presented for management of a complication of her bariatric surgery. The history goes back to September 2000 when the patient presented with a body mass index (BMI) of 45 (120 kg to 1.63 m). An adjustable gastric band was … Continue reading
Circulating and Tissue-resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function is Altered During Inflammation
Interactions between commensal microbes and the immune system are tightly regulated and maintain intestinal homeostasis, but little is known about these interactions in humans. We investigated responses of human CD4+ T cells to the intestinal microbiot… Continue reading
A Rare Cause of Pancreatitis
Question: A 32-year-old woman with a past medical history relevant for active smoking and Behçet disease diagnosed 15 years before, with vascular, articular manifestations and an acute pancreatitis that was attributed to ischemia owing to Behçet vas… Continue reading