Daily Archives: September 1, 2017

Abnormal Responses to Local Esophageal Food Allergen Injections in Adult Patients with Eosinophilic Esophagitis

Skin tests and measurement of serum levels of immunoglobulin E do not accurately identify foods for elimination from the diets of patients with eosinophilic esophagitis (EoE). We investigated whether an esophageal prick test (EPT), in which the esophag… Continue reading

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Natural Course of Unusual Primary Liver Tumor

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The Perils of Competitive Speed Eating!

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An Unusual Case of Abdominal Pain

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3D Cross-Sectional Imaging of the Inflamed Gut With Light Sheet Fluorescence Microscopy for Translational Research in IBD

The precise pathogenesis of inflammatory bowel diseases (IBD) such as Crohn’s disease (CD) or ulcerative colitis (UC) is still unclear. However, novel treatment options have become available recently1,2 and several further compounds might soon help t… Continue reading

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3D Cross-Sectional Imaging of the Inflamed Gut With Light Sheet Fluorescence Microscopy for Translational Research in IBD

The precise pathogenesis of inflammatory bowel diseases (IBD) such as Crohn’s disease (CD) or ulcerative colitis (UC) is still unclear. However, novel treatment options have become available recently1,2 and several further compounds might soon help t… Continue reading

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Anti-Tumor Necrosis Factor Therapy in Inflammatory Bowel Disease

Anti-Tumor Necrosis Factor Therapy in Inflammatory Bowel Disease is a comprehensive review of the use of anti-tumor necrosis factor (TNF) therapy in patients with inflammatory bowel disease (IBD). The book includes a preface and 35 chapters, which can … Continue reading

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Easing Concerns About the Low FODMAP Diet in Patients With Irritable Bowel Syndrome

Dietary management makes sense in patients with irritable bowel syndrome, because food is a major inducer of symptoms, and dietary manipulation empowers patients to influence the outcome of their disorder. It is not surprising, therefore, that the arri… Continue reading

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Progress in PD-1–based Immunotherapy: New Mechanistic Insight May Provide Expanded Hope for Application to Colon and Gastrointestinal Cancers

Kamphorst AO, Wieland A, Tahseen Nasti T, et al. Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent. Science 2017;355:1423-1427. Continue reading

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ROCKing the Field of Intestinal Fibrosis or Between a ROCK and a Hard Place?

Intestinal fibrosis remains one of the largest clinical challenges in the field of inflammatory bowel diseases.1 More than one-half of the patients with Crohn’s disease develop clinically apparent fibrostenosis throughout their disease course, leadin… Continue reading

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