Daily Archives: October 6, 2017

We read with interest the Matsuura et al1 genome-wide association study (GWAS) of 456 Japanese patients identifying tolloid like 1 (TLL1) as a novel susceptibility locus for hepatocellular carcinoma (HCC) after clearance of hepatitis C virus (HCV) wit… Continue reading →

We read with great interest the paper by Shabanzadeh et al1 in which the investigators conclude that screen-detected gallstones disease in the general population seems to be associated with the development of right-sided colon cancer. This is novel an… Continue reading →

Cells of the monocyte lineage contribute to tumor angiogenesis. Interleukin 35 (IL35) is a member of the IL12 family produced by regulatory, but not effector, T cells. IL35 is a dimer comprising the IL12 alpha and IL27 beta chains, encoded by IL12A and… Continue reading →

In a large cohort of an average-risk population undergoing colorectal cancer screening using fecal immunochemical testing, an increased fecal hemoglobin concentration was associated with a higher risk of subsequent colorectal advanced neoplasia. Continue reading →

Question: A 54-year-old Hispanic man presented to the hospital with several days of dizziness and nausea, associated with 2 months of fatigue and unintentional weight loss. His past medical history included hypertension, dyslipidemia, combined systolic… Continue reading →