Daily Archives: October 31, 2017
Nonalcoholic Fatty Liver Disease and Colorectal Neoplasia
Ahn JS, Sinn DH, Min YW, et al. Non-alcoholic fatty liver diseases and risk of colorectal neoplasia. Aliment Pharmacol Ther 2017;45:345-353. Continue reading
Keeping the (S)toolbox Alive Outside of the Body for Drugs Discovery
Yissachar N, Zhou Y, Ung L, et al. An intestinal organ culture system uncovers a role for the nervous system in microbe-immune crosstalk. Cell 2017;168:1135-1148. Continue reading
Will Computer-Aided Detection and Diagnosis Revolutionize Colonoscopy?
Colorectal cancer (CRC) remains a critical health concern and a significant financial burden, not only in North America, but worldwide. This highlights the importance of colonoscopy as a cost-effective means of preventing CRC through the identification… Continue reading
Human Intestinal Microbiota and Colorectal Cancer: Moving Beyond Associative Studies
Human surfaces and cavities are populated by numerous microbial communities, including bacteria, viruses, archaea, and fungi, which form a complex interactive network between themselves and the host. These inter-kingdom interactions are the result of m… Continue reading
“Spending Your Life Wisely”: How to Create an Asset Management Plan
In a recent survey of physicians under 40, only 28% reported being knowledgeable regarding personal finance and asset management.2 Less than one-quarter reported being on track for retirement, and a majority had <$100,000 in retirement savings. Although gastroenterology trainees emerge from fellowship well-trained in clinical gastroenterology, they receive little to no education about personal asset management. As such, they are often ill-prepared to make early career financial decisions that may have lasting implications. Continue reading
Enteric Glia: The Origin of Duodenal Gastrinomas?
Multiple endocrine neoplasia 1 (MEN1) is a rare autosomal-dominant disorder characterized by the development of tumors in endocrine glands and the duodenum. Duodenal gastrinomas (gastrin-secreting neuroendocrine tumors) are frequently associated with M… Continue reading
Smoking and Drinking Synergize in Pancreatitis: Multiple Hits on a Multiple Targets
Acute pancreatitis is the first stage of an inflammatory disease continuum in the pancreas that can progress through recurrent acute pancreatitis to chronic pancreatitis, and which is driven by genetic susceptibility and environmental risk factors. Alt… Continue reading
Repeal and Replace? Repair or Despair? 2017 Health Care Reform and Clinical Gastroenterology
The November 8, 2016, election propelled a single party to gain control of the presidency and both houses of congress. Similar to when the Affordable Care Act (ACA) was enacted, this provided an opportunity to reshape American health care without the n… Continue reading
Covering the Cover
In 2 large cohorts of men and women, proinflammatory diets were associated with higher risks of colorectal cancer that contained no or low peritumoral lymphocyte reactions. Continue reading