Daily Archives: November 20, 2017

Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations

Posted on November 20, 2017 by Gastroenterology Journal

Alagille syndrome is a genetic disorder characterized by cholestasis, ocular abnormalities, characteristic facial features, heart defects, and vertebral malformations. Most cases are associated with mutations in JAGGED1 (JAG1), which encodes a Notch li… Continue reading →

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Combination of Gene Expression Signature and Model for End-stage Liver Disease Score Predicts Survival of Patients With Severe Alcoholic Hepatitis

Posted on November 20, 2017 by Gastroenterology Journal

Patients with severe alcoholic hepatitis (AH) have a high risk of death within 90 days. Corticosteroids, which can cause severe adverse events, are the only treatment that increases short-term survival. It is a challenge to predict outcomes of patients… Continue reading →

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Association Between Coffee Intake After Diagnosis of Colorectal Cancer and Reduced mortality

Posted on November 20, 2017 by Gastroenterology Journal

Few studies have examined the association between coffee intake and survival after diagnosis of colorectal cancer (CRC). We performed a prospective study to investigate the association between coffee intake after a diagnosis of CRC and mortality. Continue reading →

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Prevalence of Microsatellite Instability in Intraductal Papillary Mucinous Neoplasms of the Pancreas

Posted on November 20, 2017 by Gastroenterology Journal

Microsatellite instability (MSI) due to mismatch repair deficiency (dMMR) is detected in a small proportion of pancreatic ductal adenocarcinomas (PDACs). dMMR and MSI have been associated with responses of metastatic tumors, including PDACs, to immune … Continue reading →

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