Question: A 34-year-old man with past medical history of human immunodeficiency virus (HIV) infection, presented to the hospital with complaints of dysphagia, epigastric abdominal pain, and watery diarrhea for last 2 months. This was accompanied by low-grade fever and weight loss of 20 pounds in the same time period. Patient reported noncompliance with highly active antiretroviral treatment. Routine blood work showed pancytopenia, low serum albumin level, CD4 count of 45 cells/mm3, and HIV viral load of 1,380,000 copies/mL.