Monthly Archives: December 2017
Cystic Fibrosis Colorectal Cancer Screening Consensus Recommendations
Improved therapy has substantially increased survival of persons with cystic fibrosis (CF). But the risk of colorectal cancer (CRC) in adults with CF is 5−10 times greater compared to the general population, and 25−30 times greater in CF patients … Continue reading
Information for Authors and Readers
Gastroenterology is the premiere journal in the field of gastrointestinal disease and is led by an internationally renowned board of editors. As the official journal of the AGA Institute, Gastroenterology delivers up-to-date and authoritative coverag… Continue reading
Functional Bowel Disorders: A Roadmap to Guide the Next Generation of Research
In June 2016, the National Institutes of Health hosted a workshop on functional bowel disorders (FBDs), particularly irritable bowel syndrome, with the objective of elucidating gaps in current knowledge and recommending strategies to address these gaps… Continue reading
Cost-Effectiveness of Screening Individuals With Cystic Fibrosis for Colorectal Cancer
Individuals with cystic fibrosis are at increased risk of colorectal cancer (CRC) compared to the general population, and risk is higher among those who received an organ transplant. We performed a cost-effectiveness analysis to determine optimal CRC s… Continue reading
Reshaping the Tumor Stroma for Treatment of Pancreatic Cancer
Pancreatic cancer is accompanied with a fibrotic reaction that alters interactions between tumor cells and the stroma to promote tumor progression. Consequently, strategies to target the tumor stroma might be used to treat patients with pancreatic canc… Continue reading
Pan-Genotype Hepatitis E Virus Replication in Stem Cell-derived Hepatocellular Systems
Stem cell-derived hepatocyte-like cells are permissive for pan-genotype hepatitis E virus (HEV) isolate infection. Our results reinforce the importance of using physiologically more relevant culture systems for HEV studies. Continue reading