Daily Archives: January 3, 2018

Efficacy of Laparoscopic Nissen Fundoplication vs Transoral Incisionless Fundoplication or Proton Pump Inhibitors in Patients With Gastroesophageal Reflux Disease: a Systematic Review and Network Meta-analysis

Posted on January 3, 2018 by Gastroenterology Journal

The effects of transoral incisionless fundoplication (TIF) and laparoscopic Nissen fundoplication (LNF) have been compared with those of proton pump inhibitors (PPIs) or a sham procedure in patients with gastroesophageal reflux disease (GERD), but ther… Continue reading →

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Hedgehog–YAP Signaling Pathway Regulates Glutaminolysis to Control Hepatic Stellate Cell Activation

Posted on January 3, 2018 by Gastroenterology Journal

Cirrhosis results from accumulation of myofibroblasts derived from quiescent hepatic stellate cells (Q-HSCs); it regresses when myofibroblastic HSCs are depleted. Hedgehog signaling promotes transdifferentiation of HSCs by activating Yes-associated pro… Continue reading →

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Effects of Weight Loss Medications on Cardiometabolic Risk Profiles: A Systematic Review and Network Meta-Analysis

Posted on January 3, 2018 by Gastroenterology Journal

We performed a systematic review and network meta-analysis to evaluate the overall and comparative effects of weight-loss medications, approved by the Food and Drug Administration (FDA) for long-term use, on cardiometabolic risk profiles of obese adults. Continue reading →

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