Daily Archives: January 18, 2018
P151 NONIMMUNITY AGAINST HEPATITIS B VIRUS IN PATIENTS WITH NEWLY DIAGNOSED INFLAMMATORY BOWEL DISEASE
Currently, there are no data on the prevalence rate of hepatitis B virus (HBV) serologic markers in patients with newly diagnosed inflammatory bowel disease (IBD) in Korea, which is a hepatitis B endemic area. Continue reading
P148 LACK OF INFLUENCE OF ELDERLY AGE AND GENDER ON THE SAFETY PROFILE OF BUDESONIDE EXTENDED-RELEASE TABLETS FOR ULCERATIVE COLITIS: A POOLED ANALYSIS OF TWO RANDOMIZED, DOUBLE-BLIND, PHASE 3 TRIALS
Budesonide extended-release tablets (multimatrix [MMX]) are indicated for induction of remission of mild to moderate ulcerative colitis (UC). Budesonide MMX is a second-generation corticosteroid with low systemic bioavailability related to extensive fi… Continue reading
P155 REAL-WORLD SAFETY OF VEDOLIZUMAB IN INFLAMMATORY BOWEL DISEASE: A META-ANALYSIS
Vedolizumab (VDZ) is used to treat Crohn’s disease (CD) and ulcerative colitis (UC). Data from large real-world (RW) cohorts can further characterize safety events not fully elucidated in clinical trials. Continue reading
P158 RISK FACTORS FOR NON-ADHERENCE TO BIOLOGIC THERAPIES IN INFLAMMATORY BOWEL DISEASE
Non-adherence to medications is common in patients with inflammatory bowel disease (IBD). The aim of this study was to assess adherence to biologic medications prescribed for IBD, and to identify risk factors for biologic non-adherence. Continue reading
13 REFINED POPULATION PHARMACOKINETIC MODEL FOR INFLIXIMAB PRECISION DOSING IN PEDIATRIC INFLAMMATORY BOWEL DISEASE
Standard weight-based infliximab (IFX) dosing for inflammatory bowel disease (IBD) results in long-term clinical remission in only 40-60% of patients. Patient and disease factors account for variability in IFX exposure. Achieving optimal IFX exposure a… Continue reading
P159 SEARCHING FOR MORE: THE NEED FOR HIGH-QUALITY INFORMATION AND PATIENT-CENTERED LANGUAGE IN ONLINE RESOURCES FOR MEDICAL FOODS IN IBD
Patients hoping to improve their understanding of treatments recommended by their providers frequently turn to the Internet as their source of information. Medical foods are emerging adjunct treatments in Inflammatory Bowel Diseases (IBD) with a growin… Continue reading
P154 PRIMARY NON-RESPONSE TO TUMOR NECROSIS FACTOR ANTAGONISTS IS ASSOCIATED WITH INFERIOR RESPONSE TO SECOND-LINE BIOLOGICS IN PATIENTS WITH INFLAMMATORY BOWEL DISEASES: A SYSTEMATIC REVIEW AND META-ANALYSIS
We sought to analyze whether response to second-line biologic varies depending on reason for discontinuation of primary anti-TNF agent (primary non-response [PNR], secondary loss of response [LOR] after initial response, or intolerance), through a syst… Continue reading
P160 SERUM ALBUMIN WEEK 6/WEEK 0 RATIO AFTER ANTI-TNF BEST PREDICTS BOTH SHORT- AND LONG-TERM CLINICAL OUTCOMES IN ANTI-TNF-NAïVE ULCERATIVE COLITIS PATIENTS
The aim of this study was to investigate the predictors of short- and long-term clinical response to the initial anti-TNFs in moderate to severe ulcerative colitis (UC) patients. Continue reading
P157 REPLICATING THE PATIENT’S APPROACH: A SEARCH FOR MEDICAL FOODS IN IBD
Inflammatory Bowel Disease is a group of chronic and relapsing diseases that can be associated with poor nutrient absorption. Despite the rise in biologics, there are patients unable to maintain remission. Hence there is a rising interest for medical f… Continue reading
P161 SUSTAINABLE IMPROVEMENTS IN URGENT CARE ACCESS AND OUTCOMES FOR PATIENTS WITH INFLAMMATORY BOWEL DISEASE THROUGH IMPLEMENTATION OF AN URGENT ACCESS TOOLKIT
Patients with inflammatory bowel disease (IBD) without adequate access to urgent medical care for exacerbation of symptoms tend to obtain care from emergency departments (ED), which is associated with an increased use of opiates, steroids, and poor pat… Continue reading