Daily Archives: January 18, 2018

Despite advances in medical therapy for UC, many patients still need surgery. Data on UC colectomy rates in the United States are limited. We examined colectomy rates during emergent admissions and elective ileal pouch anal anastomosis surgery (IPAA) r… Continue reading →

Fragmentation in inpatient care is prevalent among patients with chronic disease and is associated with increased mortality and readmissions. We aimed to determine the current prevalence of fragmentation among hospitalized inflammatory bowel disease pa… Continue reading →

Total proctocolectomy with creation of a pouch using a loop of small bowel followed by Ileal pouch-anal anastomosis (IPAA) is a commonly performed surgical treatment for ulcerative colitis (UC). The surgery is usually performed in 3 stages, and the ‘… Continue reading →

High levels of patient activation, defined as having the knowledge, skills, and confidence to effectively manage one’s care, has been associated with improved outcomes in many chronic conditions. We sought to evaluate the association between patient … Continue reading →

In Crohn’s disease (CD), disease severity is categorized by the Montreal classification. More complicated (stricturing and/or penetrating) disease is associated with poor quality of life. Our aim was to identify clinical, serological, and genetic fac… Continue reading →

Though pharmacokinetic studies suggest accelerated biologic drug clearance with increasing body weight, evidence of obesity’s impact on clinical outcomes in biologic-treated patients with ulcerative colitis (UC) is inconsistent. Hence, we evaluated t… Continue reading →

Cardiovascular associations of Crohn’s Disease (CD) are rare and include valvular heart disease, aortitis and aneurysm. We report an 11 year old with thoracic aortitis and aneurysm found during initial presentation of CD. Continue reading →

To assess whether obesity may affect natural history of inflammatory bowel diseases (IBD), we conducted an individual participant data (IPD) pooled analysis of placebo arms, using data from clinical trials of infliximab in IBD, using the Yale Open Data… Continue reading →

The incidence of Clostridium difficile infection (CDI) has been rising and its occurrence in Inflammatory Bowel Disease (IBD) is higher than the general population, yet there is no treatment protocol in these patients. Our study’s goal was to determine… Continue reading →

Nursing staff within a GI practice can coordinate care around IBD quality measures by checking for bone loss related to corticosteroid use, providing smoking cessation counseling, performing TB & HBV testing prior to initiating biologics, & ensuring that patients receive appropriate vaccinations. Studies continue to demonstrate care gaps around these measures. In 2016, the Postgraduate Institute for Medicine and MCM Education developed a Quality Improvement (QI) educational pilot program. This program was supported by an independent educational grant provided by Takeda Pharmaceuticals U.S.A., Inc. Continue reading →