Chronic enteropathy associated with SLCO2A1 gene (CEAS) is a rare intractable disease characterized by persistent anemia and hypoproteinemia due to multiple small intestinal ulcers. Recently, we identified that the disease is caused by loss-of-function mutations of SLCO2A1 gene, encoding a prostaglandin transporter. Because clinical features of CEAS mimic those of Crohn’s disease (CD) with respect to intestinal ulcers and stenosis, a convenient screening test other than genetic analysis is required.