Monthly Archives: January 2018

Seronegative spondyloarthopathies in inflammatory bowel disease (IBD) include ankylosing spondylitis and spondylitis associated with IBD and represent a spectrum of inflammatory axial arthropathies (IAA). Continue reading →

TNF-inhibitor (TNF) therapy was approved for use in moderately active ulcerative colitis (UC) in 2005. We were interested in studying to what extent newly approved biologics with a different mechanism of action (MOA) had on utilization. Continue reading →

Immune dysregulation is thought to be a contributing factor to the development of microscopic colitis (MC), which encompasses lymphocytic and collagenous colitis. MC pattern has been observed in colitis resulting from immunotherapy, newer agents that w… Continue reading →

Inflammatory Bowel Diseases (IBD) are known to be associated with intra- and extra-intestinal symptoms such as pelvic floor dysfunctions (PFD), fatigue, and arthopathies1. The extent to which these symptoms persist and their effects on patient quality … Continue reading →

Inflammatory bowel diseases (IBD) include two major forms of chronic intestinal disorders: Crohn’s disease (CD) and ulcerative colitis (UC). A single gold standard for the diagnosis of CD is not available. Serum protein profiling of CD was investigat… Continue reading →

Immuno-checkpoint inhibitors (ICI) are becoming an integral part of advanced cancer treatment. ICI-induced colitis (ICI-C) is one of the most common adverse events that is usually treated with steroids, infliximab or vedolizumab. All these agents are i… Continue reading →

Gut microbiota is shown to be linked with response to steroids in some diseases (bronchial asthma). Sufficient changes of intestinal microbiota composition in inflammatory bowel diseases (IBD) patients were shown by numerous investigators. Continue reading →

Immuno-checkpoint inhibitor (ICI) is becoming an integral part of advanced cancer treatment. ICI can cause adverse events in multiple organs more commonly in skin and GI tract. ICI-induced colitis (ICI-C) can be mild or severe and lead to cessation of … Continue reading →

The relationship between sleep disturbances and inflammatory conditions is incompletely understood. Studies have shown that inflammatory bowel disease (IBD) patients have poorer sleep quality, prolonged sleep latency and increased use of sleeping pills… Continue reading →

Inflammatory bowel disease (IBD) is a chronic condition characterized by periods of remission and relapses. Periodic surveys are used to monitor disease activity but are limited by their length and reliance on subjective recall. We assessed the feasibi… Continue reading →