Monthly Archives: January 2018

Question: A 45-year-old man with no significant medical history except for vague intermittent abdominal pain was referred for an endoscopic second opinion after previous colonoscopy had been pertinent for multiple segmental submucosal lesions. Previou… Continue reading →

Question: A 23-year-old woman with Budd-Chiari syndrome in treatment with warfarin was admitted to our unit because of the persistence of fever, severe abdominal pain, diarrhea, and marked weight loss. Her medical history included recurrent oral and ge… Continue reading →

We read with interest the recent systematic review and meta-analysis of anticoagulation for portal vein thrombosis (PVT) for individuals with cirrhosis from Loffredo et al.1 PVT is a frequent complication of cirrhosis and the sequelae can include mese… Continue reading →

Question: A 60-year-old Caucasian man was referred to our department for restaging of cancer of unknown primary syndrome with peritoneal carcinosis (confirmed by diagnostic laparoscopy), which had been diagnosed 8 months before. The patient had already… Continue reading →

We believe that some further comment would be appropriate about the interesting systematic review and meta-analysis on the effects of anticoagulants in patients with cirrhosis and portal vein thrombosis (PVT), recently published in Gastroenterology.1 O… Continue reading →

The trial by Pinto-Sanchez et al1 published in a recent issue of Gastroenterology reports a relationship between probiotic Bifidobacterium longum NCC3001 and a decrease in depression scores in patients with irritable bowel syndrome (IBS). IBS is consi… Continue reading →

We thank Drs Meyer and Vassar for their interest in our study1 and comments on the use of the Fragility Index (FI). We agree that FI may be useful as an intuitive measure of the robustness of randomized, control trials2; however, caution needs to be ex… Continue reading →

Question: An 82-year-old asymptomatic man presented with an incidental finding of liver lesion on a computed tomography (CT) angiogram performed for infrarenal abdominal aortic aneurysm repair surveillance. He had a history of bladder cancer 7 years pr… Continue reading →

A recent systematic review with meta-analysis by Loffredo et al1 updated our previous findings2 regarding the use of anticoagulation for the treatment of portal vein thrombosis (PVT) in patients with liver cirrhosis. However, when the original papers … Continue reading →

As the prologue to the first edition of Sternberg’s Surgical Pathology states, the surgical pathologist’s career can be very lonely. Our working environment is characterized by our relationship with our microscopes, our books becoming companions in… Continue reading →