Monthly Archives: January 2018
Enteritis and Rapid-Onset Renal Dysfunction in a Previously Healthy Adult
Question: A 49-year-old Caucasian man with a past medical history of hyperlipidemia presented with colicky, generalized abdominal pain of 3 weeks’ duration. He had traveled to Mexico 3 months prior; however, he denied sick contacts or antibiotic usag… Continue reading
Histologic Factors Associated With Need for Surgery in Patients With Pedunculated T1 Colorectal Carcinomas
Most patients with pedunculated T1 colorectal tumors referred for surgery are not found to have lymph node metastases, and were therefore unnecessarily placed at risk for surgery-associated complications. We aimed to identify factors associated with ne… Continue reading
Lamin A/C Maintains Exocrine Pancreas Homeostasis by Regulating Stability of RB and Activity of E2F
Lamins have important roles in nuclear structure and cell signaling. Several diseases are associated with mutations in the lamin A/C gene (LMNA in humans). Patients with familial partial lipodystrophy caused by LMNA mutations develop pancreatitis, but … Continue reading
Bi-directionality of Brain–Gut Interactions in Patients With Inflammatory Bowel Diseases
Inflammatory bowel diseases (IBD) are associated with mood disorders, such as anxiety or depression, but it is not clear whether one contributes to development of the other, or if the interaction is bi-directional (anxiety or depression contributes to … Continue reading
Association Between Portosystemic Shunts and Increased Complications and Mortality in Patients With Cirrhosis
Spontaneous portosystemic shunts (SPSSs) have been associated with hepatic encephalopathy (HE). Little is known about their prevalence among patients with cirrhosis or clinical effects. We investigated the prevalence and characteristics of SPSSs in pat… Continue reading
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