Daily Archives: February 28, 2018

Analysis of Genes Associated with Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn’s disease

Posted on February 28, 2018 by Gastroenterology Journal

A few rare monogenic primary immunodeficiencies (PID) are characterized by chronic intestinal inflammation that resembles Crohn’s disease (CD). We investigated whether 23 genes associated with 10 of these monogenic disorders contain common, low-frequ… Continue reading →

Posted in News | Comments Off on Analysis of Genes Associated with Monogenic Primary Immunodeficiency Identifies Rare Variants in XIAP in Patients With Crohn’s disease

Change in Populations of Macrophages Promotes Development of Delayed Gastric Emptying in Mice

Posted on February 28, 2018 by Gastroenterology Journal

Muscularis propria macrophages lie close to cells that regulate gastrointestinal motor function, including interstitial cells of Cajal (ICC) and myenteric neurons. In animal models of diabetic gastroparesis, development of delayed gastric emptying has … Continue reading →

Posted in News | Comments Off on Change in Populations of Macrophages Promotes Development of Delayed Gastric Emptying in Mice