Daily Archives: March 8, 2018

The recognition that the hyperinsulinemic state is associated with the metabolic syndrome or type II diabetes mellitus is linked with increased colorectal cancer risk has led to studies of antidiabetes drugs to prevent cancer.1 Metformin has multiple a… Continue reading →

I read with interest the article by Lens et al1 regarding the use of all-oral antiviral therapy on the effects of hepatic venous pressure gradient (HVPG) in patients with hepatitis C virus infection. I would like to congratulate Dr Lens and his collab… Continue reading →

I read the article of Chai et al1 with great interest. The authors have shown that the beneficial role of miR-122 induced by free fatty acids (FFA) in the reduction of triglyceride accumulation in the liver and muscle was mediated through retinoid-rel… Continue reading →

VanWagner et al1 performed a post hoc analysis from the CARDIA cohort study (Coronary Artery Risk Development in Young Adults Study) and found that 58% of the patients with nonalcoholic fatty liver disease self-reported “moderate alcohol” use. Thi… Continue reading →

We read with interest the article entitled “Baseline Parameters in Clinical Trials for Nonalcoholic Steatohepatitis: Recommendations From the Liver Forum” by Patel et al.1 We congratulate the authors on a very well-done and in-depth presentation o… Continue reading →

We are grateful to Professor Craig for the comments on our recently published article. We agree this is important research that addresses some of the limitations of previous trials of the low FODMAP diet, including our use of dietary advice as the inte… Continue reading →

The article by Kanwal et al1 in the October issue of Gastroenterology is of utmost importance. It clearly shows that the cure of chronic infection by hepatitis C virus with direct-acting antivirals reduced the risk of developing hepatocellular carcino… Continue reading →

We thank Dr Mandorfer and Dr Gin-Ho Lo for their thorough reading of our manuscript. Continue reading →

Staudacher et al1 have done important work on extending information on FODMAP restriction in subjects with diarrhea-predominant irritable bowel syndrome. There are 3 issues that require some additional attention. First, the investigators used as their… Continue reading →

We thank Hsien-Hui Chung for his interest in our publication.1 We have read his arguments and we offer our response. In contrast with our results, showing increased lipid metabolism after inhibition of miR-122, a previous report by Esau et al,2 showed… Continue reading →