Daily Archives: March 10, 2018
Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll Like Receptor 3 in Hepatocytes
Hepatitis C virus (HCV) infections often persist lifelong. We have identified a novel viral immune evasion mechanism based on the secretion of viral double stranded RNA from infected cells in extracellular vesicles. Thereby the virus is less efficientl… Continue reading
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Baseline Factors Associated with Improvements in Decompensated Cirrhosis After Direct-acting Antiviral Therapy for HCV Infection
Treatment with direct-acting antiviral (DAA) agents can reduce model for end-stage liver disease and Child-Pugh-Turcotte (CPT) scores in patients with decompensated cirrhosis caused by hepatitis C virus (HCV). However, many of these patients still die … Continue reading
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