Monthly Archives: March 2018
Intestinal failure and aberrant lipid metabolism in patients with DGAT1 deficiency
Congenital diarrheal disorders are rare inherited intestinal disorders characterized by intractable, sometimes life-threatening, diarrhea and nutrient malabsorption; some have been associated with mutations in diacylglycerol-acyltransferase 1 (DGAT1), … Continue reading
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Alphafetoprotein: why won’t it go gentle into the good night?
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Identification of Endpoints for Development of Anti-fibrosis Drugs for Treatment of Crohn’s Disease
Intestinal fibrosis is a challenge to management of patients with Crohn’s disease (CD); there is an urgent need to expedite development of anti-fibrosis drugs for this disease. The International Organization for the Study of Inflammatory Bowel Diseas… Continue reading
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Identification of Variants in RET and IHH Pathway Members in a Large Family With History of Hirschsprung Disease
Hirschsprung disease (HSCR) is an inherited congenital disorder characterized by absence of enteric ganglia in the distal part of the gut. Variants in ret proto-oncogene (RET) have been associated with up to 50% of familial and 35% of sporadic cases. W… Continue reading
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The Tangled Web of Interactions Between Host, Pathogen, and Microbiota in Clostridium difficile Infection
It has been well-established that the gut microbiota, the indigenous microbes of the gastrointestinal tract, is intimately involved in susceptibility to colonization and infection with Clostridium difficile, an important health care-associated pathogen… Continue reading
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Thirty-day Readmission Among Patients With Non-variceal Upper Gastrointestinal Hemorrhage and Effects on Outcomes
We aimed to determine the rate of hospital readmission within 30 days of non-variceal upper gastrointestinal hemorrhage (NVUGIH) and its impact on mortality, morbidity and healthcare utilization in the United States. Continue reading
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Should presence of spontaneous portosystemic shunts be implemented to the MELD-score for a better prediction of outcome?
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Limited submission opportunity: Phi Beta Psi Charity Trust Cancer Research Grant
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Good Friday and Easter services planned for Children’s Hospital Chapel
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Passover exhibit in Central Library, March 29-April 8
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