Daily Archives: April 2, 2018

Hepatitis C virus (HCV) is an established cause of chronic liver disease worldwide. Owing to the advent of highly effective therapy, high age-group seroprevalence, and many estimated missed cases, HCV screening recommendations for Baby Boomers (those b… Continue reading →

With great interest we read the study by Nikolaus et al1 concluding that increased tryptophan (TRP) metabolism is associated with disease activity of inflammatory bowel disease (IBD).1 We agree with the authors that there remains an unmet need for non… Continue reading →

We read with great interest the manuscript by Mazzaferro et al1 entitled “Metroticket 2.0 Model for Analysis of Competing Risks of Death Following Liver Transplantation for Hepatocellular Carcinoma.” The authors established a preoperatively assess… Continue reading →

We read with great interest the recently published study on Chronic Pancreatitis Prognosis Score reported by Beyer et al.1 We concur that a model to assess disease severity or progression, or to predict patient outcomes is of significant importance. H… Continue reading →

We thank Hao et al for commenting on the Chronic Pancreatitis Prognosis Score (COPPS).1 The aim for developing COPPS was to identify readily available parameters that correspond with the short- and medium-term clinical outcomes of chronic pancreatitis… Continue reading →

We read with much interest the published article entitled “A Panel of Methylated MicroRNA Biomarkers for Identifying High-Risk Patients with Ulcerative Colitis-Associated Colorectal Cancer” by Toiyama et al.1 At this juncture, we wish to express o… Continue reading →

I read with great interest for the article by Satishchandran et al.1 The authors have shown that the beneficial role of hepatic miR-122 in patients and mice with alcoholic liver disease (ALD) was modulated by grainyhead-like transcription factor 2 (GR… Continue reading →

Inflammation affects regeneration of the intestinal epithelia; long non-coding RNAs (lncRNAs) regulate cell functions such as proliferation, differentiation, and migration. We investigated the mechanisms by which the lncRNA H19, imprinted maternally ex… Continue reading →

Although attainment of a sustained virologic response (SVR) reduces the incidence of hepatocellular carcinoma (HCC) in patients with chronic hepatitis C virus (HCV) infection, increased risk of HCC remains.1 In the largest series to date, risk factors … Continue reading →