Daily Archives: May 4, 2018

MAF bZIP transcription factor G (MAFG) is activated by the farnesoid X receptor (FXR) to repress bile acid synthesis. However, expression of MAFG increases during cholestatic liver injury in mice and in cholangiocarcinomas. MAFG interacts directly with… Continue reading →

The Julius Friedenwald Medal honors an individual who has made lifelong contributions to the field of gastroenterology and contributed significantly to the American Gastroenterological Association (AGA). This is the highest honor bestowed by the AGA, a… Continue reading →

Little is known about the natural course of nonalcoholic fatty liver disease (NAFLD) with advanced fibrosis. We describe long-term outcomes and evaluate the effects of clinical and histologic parameters on disease progression in patients with advanced … Continue reading →

As of December 27, 2017, the medical world is a different place. There is a void left by the departure of Dr Horatio Jinich. He was a great humanitarian: a superb physician, thinker, communicator, and medical expert. Continue reading →

The physical properties of the extracellular environment such as matrix composition and mechanics are key factors that determine cancer cell behavior.1,2 Stiffening matrix is a result of a complex multidirectional interplay between stromal cells such a… Continue reading →

Personalized medicine is based on the concept that predictive tests support clinical decision making, allowing individualized interventions and improving patient outcomes. Genetic data can inform this process. Patients with inflammatory bowel disease (… Continue reading →

In patients with achalasia esophagus, swallows induce simultaneous pressure waves known as esophageal pressurization. We studied the mechanism of esophageal pressurization and bolus flow patterns in patients with type 2 or type 3 achalasia. Continue reading →