Daily Archives: May 11, 2018

Molecular Background of Colorectal Tumors From Patients with Lynch Syndrome Associated With Germline Variants in PMS2

Germline variants in the mismatch repair genes MLH1, MSH2 (EPCAM), MSH6, or PMS2 cause Lynch syndrome. Patients with these variants have an increased risk of developing colorectal cancers (CRCs) that differ from sporadic CRCs in genetic and histologic … Continue reading

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Increased Long-term Dietary Fiber Intake is Associated With Decreased Risk of Fecal Incontinence in Older Women

Fiber supplements are frequently used as treatment for fecal incontinence (FI), but little is known about role of dietary fiber in the prevention of FI. Continue reading

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