Monthly Archives: May 2018

“My philosophy is, I am a patient myself. What if someone is in pain when they call? What if they’re scared? The team does anything we can to help them.” Continue reading →

The picnic is an opportunity for VUMC to show appreciation for employees who make our organization a success.
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Biomarkers are needed for early detection of Crohn’s disease (CD) and ulcerative colitis (UC) or to predict patient outcomes. Glycosylation is a common and complex post-translational modification of proteins that affects their structure and activity…. Continue reading →

Crohn’s disease (CD) presents as chronic and often progressive intestinal inflammation, but the contributing pathogenic mechanisms are unclear. We aimed to identify alterations in intestinal cells that could contribute to the chronic and progressive … Continue reading →

Strategies are needed to increase gastrointestinal transit without systemic pharmacologic agents. We investigated whether optogenetics, focal application of light to control enteric nervous system excitability, could be used to evoke propagating contra… Continue reading →

Defects in lysosome function and autophagy contribute to pathogenesis of alcoholic liver disease. We investigated the mechanisms by which alcohol consumption affects these processes, evaluating the functions transcription factor EB (TFEB), which regula… Continue reading →

There are marked racial and ethnic differences in noncardia gastric cancer prevalence within the United States (US). Although gastric cancer screening is recommended in regions of high prevalence, screening is not routinely performed in the US. Our obj… Continue reading →

Patients with thrombocytopenia and chronic liver disease (CLD) may require platelet transfusions before scheduled procedures to decrease risk of bleeding. We performed 2 randomized, placebo-controlled, phase 3 trials in patients with thrombocytopenia a… Continue reading →