Daily Archives: June 8, 2018

More Than One Culprit for Nonceliac Gluten/Wheat Sensitivity

We read with interest the article by Skodje et al1 reporting a double-blind placebo-controlled food challenge aimed at establishing whether gluten or fructan, a component of fermentable oligo-, di-, monosaccharides and polyols, evokes gastrointestinal… Continue reading

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New Management Guidelines for Both Children and Adults With Acute Pancreatitis

We read with great interest the American Gastroenterological Association’s (AGA) updated guidelines on the management of acute pancreatitis (AP)1 and its accompanying technical review.2 AP is the most common pancreatic disease across the globe, occurring in >17 million persons in 2013.3 As such, AP ranks as the top gastroenterologic reason for hospitalization, incurring >$2.6 billion in inpatient costs.4 Since the prior AGA AP guidelines were published in 2007,5 there have been >5000 manuscripts published on AP. Continue reading

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The Diagnosis Effect of DNA Methylation in Inflammatory Bowel Diseases

We read with great interest the article by Howell et al,1 who presented the findings of DNA methylation and transcription pattern in intestinal epithelial cells of children with inflammatory bowel disease (IBD). The authors concluded that there are ep… Continue reading

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CME Exam 1: A Young Man With Epigastric Pain After Extracorporeal Shock Wave Lithotripsy

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The Discrimination of Inflamed Versus Uninflamed Tissue: Combining Histology and Molecular Techniques

We read with great interest the detailed and informative investigation of multi-omics analysis of intestinal epithelial cells (IEC) collected from pediatric patients with inflammatory bowel disease by Howell et al.1 The authors have shown specific pro… Continue reading

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CME Exam 2: Improvement in Gastrointestinal Symptoms After Cognitive-Behavioral Therapy for Refractory Irritable Bowel Syndrome

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CME Exam 3: Improved Diet Quality Associates With Reduction in Liver Fat, Particularly in Individuals With High Genetic Risk Scores for Nonalcoholic Fatty Liver Disease

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