Daily Archives: June 8, 2018
More Than One Culprit for Nonceliac Gluten/Wheat Sensitivity
We read with interest the article by Skodje et al1 reporting a double-blind placebo-controlled food challenge aimed at establishing whether gluten or fructan, a component of fermentable oligo-, di-, monosaccharides and polyols, evokes gastrointestinal… Continue reading
New Management Guidelines for Both Children and Adults With Acute Pancreatitis
We read with great interest the American Gastroenterological Association’s (AGA) updated guidelines on the management of acute pancreatitis (AP)1 and its accompanying technical review.2 AP is the most common pancreatic disease across the globe, occurring in >17 million persons in 2013.3 As such, AP ranks as the top gastroenterologic reason for hospitalization, incurring >$2.6 billion in inpatient costs.4 Since the prior AGA AP guidelines were published in 2007,5 there have been >5000 manuscripts published on AP. Continue reading
The Diagnosis Effect of DNA Methylation in Inflammatory Bowel Diseases
We read with great interest the article by Howell et al,1 who presented the findings of DNA methylation and transcription pattern in intestinal epithelial cells of children with inflammatory bowel disease (IBD). The authors concluded that there are ep… Continue reading
CME Exam 1: A Young Man With Epigastric Pain After Extracorporeal Shock Wave Lithotripsy
The Discrimination of Inflamed Versus Uninflamed Tissue: Combining Histology and Molecular Techniques
We read with great interest the detailed and informative investigation of multi-omics analysis of intestinal epithelial cells (IEC) collected from pediatric patients with inflammatory bowel disease by Howell et al.1 The authors have shown specific pro… Continue reading