Daily Archives: June 14, 2018

NFκB in Pancreatic Stellate Cells Reduces Infiltration of Tumors by Cytotoxic T Cells and Killing of Cancer Cells, via Upregulation of CXCL12

Immunotherapies are ineffective against pancreatic cancer. We investigated whether the activity of nuclear factor (NF)κB in pancreatic stromal cells contributes to an environment that suppresses anti-tumor immune response. Continue reading

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Diet Modifies Colonic Microbiota and CD4+ T Cell Repertoire to Induce Flares of Colitis in Mice With Myeloid-cell Expression of Interleukin 23

Several studies have shown that signaling via the interleukin 23 (IL23) receptor is required for development of colitis. We studied the roles of IL23, dietary factors, alterations to the microbiota, and T cells in development and progression of colitis… Continue reading

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Efficacy of Ustekinumab in Inducing Endoscopic Healing in Patients with Crohn’s Disease

We evaluated the ability of ustekinumab, a monoclonal antibody against the p40 subunit of interleukins 12 and 23, to induce endoscopic healing in patients with moderate to severe Crohn’s disease (CD). Continue reading

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Children with autism 8-14 years of age needed for study on sound processing

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Herbs are now available to employees in the VUMC Community Garden

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Friends Shop summer sale begins today

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“What is Home Health Care?” presentation is tomorrow

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Medical Center Staff Advisory Council meeting is July 17

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Abdulahad named Executive Vice President and Chief Development Officer for Medical Center

Zeena M. Abdulahad, Vice President of Development at Memorial Sloan Kettering Cancer Center in New York, has been named Vanderbilt University Medical Center’s new Executive Vice President and Chief Development Officer. Abdulahad will join VUMC Sept. 1. Continue reading

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Children 5 to 12 years old needed for myopia treatment study

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