Daily Archives: June 20, 2018

Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine

The glucagon like peptide 1 (GLP1) is produced by L cells in the intestine, and agonists of the GLP1 receptor are effective in treatment of diabetes. Levels of GLP1 increase with numbers of L cells. Agents that increase numbers of L cell might therefor… Continue reading

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Number of Adenomas Removed and Colorectal Cancers Prevented in Randomized Trials of Flexible Sigmoidoscopy Screening

Screening for colorectal cancer (CRC) with sigmoidoscopy reduces CRC incidence by detecting and removing adenomas. The number needed to screen is a measure of screening efficiency, but is not directly associated with adenoma removal. We propose 2 new m… Continue reading

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