We read with great interest the American Gastroenterological Association’s (AGA) updated guidelines on the management of acute pancreatitis (AP)1 and its accompanying technical review.2 AP is the most common pancreatic disease across the globe, occurring in >17 million persons in 2013.3 As such, AP ranks as the top gastroenterologic reason for hospitalization, incurring >$2.6 billion in inpatient costs.4 Since the prior AGA AP guidelines were published in 2007,5 there have been >5000 manuscripts published on AP.