Monthly Archives: July 2018
Solorzano named interim chair of Department of Surgery
Carmen Solorzano, MD, professor of Surgery and Chief of the Division of Surgical Oncology and Endocrine Surgery, has been named the interim chair of Vanderbilt’s Department of Surgery. Continue reading
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New audiology clinic debuts in Green Hills
Adult patients now have a convenient new option for hearing evaluations, hearing aid consultations and fittings and other services with the opening of a new audiology clinic in Green Hills.
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Alzheimer’s gene screening event set for Aug. 3
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Message from President and CEO about offensive email
Dear Colleagues — As some of you are aware, an offensive email was sent from an external source to members of the Vanderbilt community overnight. Both University and Medical Center employees have been recipients of an email containing racist language … Continue reading
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Message from President and CEO about email system hack
Dear Colleagues — As some of you are aware, the University’s email system was hacked overnight, and both University and Medical Center employees have been recipients of an email containing racist language that is disgusting and hurtful to the Vanderbi… Continue reading
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Activated ATF6 Induces Intestinal Dysbiosis and Innate Immune Response to Promote Colorectal Tumorigenesis
Activating transcription factor 6 (ATF6) regulates endoplasmic reticulum stress. We studied whether ATF6 contributes to the development of colorectal cancer (CRC) using tissue from patients and transgenic mice. Continue reading
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Deletion of Stearoyl-CoA Desaturase-1 From the Intestinal Epithelium Promotes Inflammation and Tumorigenesis, Reversed by Dietary Oleate
The enzyme stearoyl-coenzyme A desaturase 1 (SCD or SCD1) produces mono-unsaturated fatty acids by introducing double bonds into saturated bonds between carbons 9 and 10, with oleic acid as the main product. SCD1 is present in the intestinal epithelium… Continue reading
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Routine molecular analysis for Lynch syndrome among adenomas or colorectal cancer within a national screening program
It is important to identify individuals with Lynch syndrome because surveillance programs can reduce their morbidity and mortality from colorectal cancer (CRC). We assessed the diagnostic yield of immunohistochemistry to detect Lynch syndrome in patien… Continue reading
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Solute Carrier Organic Anion Transporter Family Member 3A1 is a Bile Acid Efflux Transporter in Cholestasis
Bile acid transporters maintain bile acid homeostasis. Little is known about the functions of some transporters in cholestasis or their regulatory mechanism. We investigated the hepatic expression of solute carrier organic anion transporter family memb… Continue reading
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No Difference in Colorectal Cancer Incidence or Stage at Detection by Colonoscopy Among 3 Countries With Different Lynch Syndrome Surveillance Policies
Patients with Lynch syndrome are at high risk for developing colorectal cancer (CRC). Regular colonoscopic surveillance is recommended, but there is no international consensus on the appropriate interval. We investigated whether shorter intervals are a… Continue reading
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