Monthly Archives: July 2018

De novo lipogenesis is increased in livers of patients with nonalcoholic steatohepatitis (NASH). Acetyl-CoA carboxylase catalyzes the rate-limiting step in this process. We evaluated the safety and efficacy of GS-0976, an inhibitor of acetyl-CoA carbox… Continue reading →

Although recurrent diverticular hemorrhage is common, its incidence and risk factors have not been measured outside of small institutional cohorts. We analyzed the incidence of and risk factors for recurrent diverticular hemorrhage and whether disconti… Continue reading →

It is unclear whether participation in competency-based fellowship programs for endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) result in high-quality care in independent practice. We aimed to measure quality indic… Continue reading →

The model for end-stage liver disease-sodium (MELD-Na) score was introduced for liver allocation in January 2016. We evaluated the effects of liver allocation, based on MELD-Na score, on waitlist and post-transplant outcomes. Continue reading →

The intestinal epithelium is maintained by intestinal stem cells (ISCs), which produce post-mitotic absorptive and secretory epithelial cells. Initial fate specification toward enteroendocrine, goblet, and Paneth cell lineages requires the; transcripti… Continue reading →

Although different brands of fecal immunochemical tests (FITs) are used for colorectal cancer (CRC) screening, few studies have compared their accuracy in detecting advanced neoplasia. Continue reading →

Cirrhosis and its clinical consequences can be aggravated by bacterial infections, ultimately leading to the development of acute on chronic liver failure (ACLF), characterized by acute decompensation, organ failure, and high mortality within 28 days. … Continue reading →

A collaborative program across units at Vanderbilt University Medical Center and Monroe Carell Jr. Children’s Hospital at Vanderbilt is changing the way nurses and doctors care for newborns diagnosed with drug withdrawal symptoms at birth, also known a… Continue reading →

No single approach will end the epidemic of fatal overdoses caused by addiction to opioid painkillers and heroin that is ravaging this country, the U.S. Assistant Secretary for Health, Adm. Brett Giroir, MD, warned Tuesday during a panel discussion in … Continue reading →

First lady Melania Trump visited Monroe Carell Jr. Children’s Hospital at Vanderbilt Tuesday to learn firsthand about Team Hope, Vanderbilt’s multidisciplinary team focused on helping infants born with neonatal abstinence syndrome (NAS) as well as thei… Continue reading →