Monthly Archives: August 2018
CME Exam 1: New Onset Hematochezia in a Post-Transplant Patient
CME Exam 2: Chronic Abdominal Pain in a 47-Year-Old Woman
CME Exam 4: Model to Determine Risk of Pancreatic Cancer in Patients With New-onset Diabetes
Immune Cell and Stromal Signature Associated with Progression-free Survival of Patients with Resected Pancreatic Ductal Adenocarcinoma
Changes to the microenvironment of pancreatic ductal adenocarcinomas (PDACs) have been associated with poor outcomes of patients. We studied the associations between composition of the pancreatic stroma (fibrogenic, inert, dormant, or fibrolytic stroma… Continue reading
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Drs Khalaf et al1 have provided an analysis of regular use of aspirin and risk of pancreatic cancer in the Health Professionals Follow-up Study and the Nurses’ Health Study (NHS), two substantial cohort studies. Given that these 2 studies were recen… Continue reading
Association Between Proton Pump Inhibitor Use and Risk of Stroke
We read with interest the article by Nguyen et al1 evaluating the association between proton pump inhibitor (PPI) use and ischemic stroke. The authors found that PPI use was associated with a significant increase in the risk of ischemic stroke after a… Continue reading
Possible Autocrine Function of Galectin-3 in Pancreatic Stellate Cells
We read with great interest the recent report of Zhao et al.1 The authors have provided experimental evidence that shows the effect of exogenous galectin-3 (GAL3) on pancreatic stellate cell (PSC) activation and its consequence on the pancreatic ducta… Continue reading
CME Exam 3: Exposure Concentrations of Infants Breastfed by Women Receiving Biologic Therapies for Inflammatory Bowel Diseases and Effects of Breastfeeding on Infections and Development
Efficacy of Laparoscopic Nissen Fundoplication vs Transoral Incisionless Fundoplication or Proton Pump Inhibitors in Patients With Gastroesophageal Reflux Disease: Misleading Ranking Probabilities in Network Meta-analysis
We read the systematic review and network meta-analysis published in the Journal by Richter et al1 regarding the efficacy of laparoscopic Nissen fundoplication (LNF) versus transoral incisionless fundoplication (TIF) or proton pump inhibitors (PPIs) i… Continue reading