Daily Archives: November 1, 2018

MEK Inhibitor Reverses Metaplasia and Allows Re-emergence of Normal Lineages in Helicobacter pylori-infected Gerbils

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Superiority of Step-up Approach vs Open Necrosectomy in Long-term Follow up of Patients With Necrotizing Pancreatitis

In a 2010 randomized trial (the PANTER trial), a surgical step-up approach for infected necrotizing pancreatitis was found to reduce the composite endpoint of death or major complications compared with open necrosectomy; 35% of patients were successful… Continue reading

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Single-cell RNA Sequencing of Blood and Ileal T cells From Patients With Crohn’s Disease Reveals Tissue-specific Characteristics and Drug Targets

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Impaired Exocrine Pancreatic Function Associates With Changes in Intestinal Microbiota Composition and Diversity

Changes in intestinal microbiome composition are associated with inflammatory, metabolic, and malignant disorders. We studied how exocrine pancreatic function affects intestinal microbiota. Continue reading

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What is Needed to Eliminate Hepatitis B Virus and Hepatitis C Virus as Global Health Threats

Hepatitis B virus (HBV) and hepatitis C virus (HCV) cause 1.3 million deaths annually. To prevent over 7 million deaths by 2030, the World Health Organization set goals to eliminate HBV and HCV, defined as a 90% reduction in new infections and a 65% re… Continue reading

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